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Chronic adult primary immune thrombocytopenia (ITP) in the Asia-Pacific region.

Authors
  • Heng, Lee Lai1
  • Caguioa, Priscilla2
  • Chin, Ng Soo3
  • Chiou, Tzeon-Jye4, 5
  • Lee, Jong Wook6
  • Miyakawa, Yoshitaka7
  • Tambunan, Karmel L8
  • Chong, Beng H9
  • 1 Singapore General Hospital, Singapore, Singapore. , (Singapore)
  • 2 University of Stanto Tomas Hospital, Manila, Philippines. , (Philippines)
  • 3 Sime Darby Medical Centre, Subang Jaya, Malaysia. , (Malaysia)
  • 4 Taipei Veterans General Hospital, National Young-Ming University School of Medicine, National Defense Medical Center, Taipei, Taiwan. , (Taiwan)
  • 5 Hematology Society of Taiwan, Taipei, Taiwan. , (Taiwan)
  • 6 The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea. , (North Korea)
  • 7 Keio University, Tokyo, Japan. , (Japan)
  • 8 University of Indonesia, Jakarta, Indonesia. , (Indonesia)
  • 9 St George Clinical School, University of New South Wales, St George Hospital, Level 2 Pitney Building, Belgrave Street, Kogarah, Sydney, NSW, 2217, Australia. [email protected] , (Australia)
Type
Published Article
Journal
International Journal of Hematology
Publisher
Springer-Verlag
Publication Date
Aug 01, 2011
Volume
94
Issue
2
Pages
142–149
Identifiers
DOI: 10.1007/s12185-011-0894-8
PMID: 21766185
Source
Medline
License
Unknown

Abstract

Patients with primary immune thrombocytopenia (ITP) from the Asia-Pacific region often exhibit characteristics distinct from those of patients from the West. Moreover, as the region itself is heterogeneous, the ITP landscape among individual Asia-Pacific countries can be diverse. The recently released international consensus report on ITP places new emphasis on ITP, but does not address the unique ITP landscape in the Asia-Pacific region, which is home to 60% of the world's population. In an attempt to characterize how the ITP landscape differs between the West and the Asia-Pacific region, an expert panel with representatives from Northeast Asia, Southeast Asia, and Australia was convened. Important differences were identified between the guidance provided in the international consensus report and experience in the Asia-Pacific region, namely diagnostic practices, incidence and approach to ITP secondary to H. pylori infection, systemic lupus erythematosus-related ITP, the use of bone marrow examination, initial treatment strategies, and the role of splenectomy, rituximab, and thrombopoietin receptor agonists.

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