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Chromosomal changes in renal cell carcinoma. No evidence for correlation with clinical stage.

Authors
Type
Published Article
Journal
Cancer Genetics and Cytogenetics
0165-4608
Publisher
Elsevier
Publication Date
Volume
45
Issue
2
Pages
197–205
Identifiers
PMID: 2317768
Source
Medline

Abstract

A cytogenetic study was performed in 18 renal cell carcinomas using a culture method previously described. The significance of chromosome involvement in clonal aberrations was evaluated according to the mean + 1 SD objective criterion. Chromosomes 3, 7, 9, and 17 were preferentially involved in both numerical and structural changes. The cytogenetic data have been correlated with the clinical staging, but in contrast to a previous study, abnormalities of chromosome 3 were not associated with a higher clinical stage.

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