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Chromosomal changes in renal cell carcinoma. No evidence for correlation with clinical stage.

Authors
  • Teyssier, J R1
  • Ferre, D
  • 1 Histology-Embryology-Cytogenetics Laboratory, Faculty of Medicine, INSERM U314, Reims, France. , (France)
Type
Published Article
Journal
Cancer Genetics and Cytogenetics
Publisher
Elsevier
Publication Date
Apr 01, 1990
Volume
45
Issue
2
Pages
197–205
Identifiers
PMID: 2317768
Source
Medline
License
Unknown

Abstract

A cytogenetic study was performed in 18 renal cell carcinomas using a culture method previously described. The significance of chromosome involvement in clonal aberrations was evaluated according to the mean + 1 SD objective criterion. Chromosomes 3, 7, 9, and 17 were preferentially involved in both numerical and structural changes. The cytogenetic data have been correlated with the clinical staging, but in contrast to a previous study, abnormalities of chromosome 3 were not associated with a higher clinical stage.

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