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Chromatin-remodeling links metabolic signaling to gene expression

Authors
  • Morrison, Ashby J.
Type
Published Article
Journal
Molecular Metabolism
Publisher
Elsevier BV
Publication Date
Mar 16, 2020
Volume
38
Identifiers
DOI: 10.1016/j.molmet.2020.100973
PMID: 32251664
PMCID: PMC7300377
Source
PubMed Central
Keywords
License
Unknown

Abstract

• Chromatin modifications facilitate responsive, rapid, and reversible gene expression. • Chromatin remodelers regulate metabolic gene expression and cell division in response to changing nutrient environments. • Metabolic signaling pathways, such as the TOR pathway, cooperate with chromatin-remodeling. • Chromatin remodelers control gene expression programs in developing tissues with diverse metabolic requirements.

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