Choroidal melanoma metastasizing to maxillofacial bones

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Choroidal melanoma metastasizing to maxillofacial bones

Publisher
BioMed Central
Publication Date
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PMC
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Disciplines
  • Medicine
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Abstract

1477-7819-5-30.fm ral World Journal of Surgical Oncology ss BioMed Cent Open AcceCase report Choroidal melanoma metastasizing to maxillofacial bones Manoj Pandey*1,4, Om Prakash5, Anitha Mathews2, Nileena Nayak2 and Krishnankutty Ramachandran3 Address: 1Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India, 2Pathology, Regional Cancer Centre, Trivandrum, Kerala, India, 3Imagiology, Regional Cancer Centre, Trivandrum, Kerala, India, 4Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India and 5Oral and Maxillofacial Surgery, Government Dental College, Thiruvananthapuram, India Email: Manoj Pandey* - [email protected]; Om Prakash - [email protected]; Anitha Mathews - [email protected]; Nileena Nayak - [email protected]; Krishnankutty Ramachandran - [email protected] * Corresponding author Abstract Background: Melanomas are malignant neoplasm of melanocytic origin, commonly seen on skin and various mucous membranes. Melanomas are the commonest intraocular malignant tumour in the adults. Case presentation: A 50-year-old female presented with complains of painless progressive swelling in right cheek region of two months duration. Examination revealed a 6 × 4 cm bony hard swelling in right zygomatic region near and below lateral canthus of right eye with loss of vision. Investigations revealed it to be a choroidal melanoma metastatising to the zygomatic bone. Patient was successfully treated by surgery. Conclusion: Choroidal melanoma, which commonly metastasizes to liver and lungs, never involves the lymph nodes and metastasis to facial bones is rare. Here we report a case of choroidal melanoma metastasizing to maxillofacial bones. Background Choroidal melanoma is the most common primary intraocular malignant tumour [1]. They arise from uveal melanocytes residing in the uveal stroma and originating from the neural crest [2]. Choridal melanomas are quite different from their cutaneous coun

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