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Choosing a macrolide: drug interactions must be taken into account.

Type
Published Article
Journal
Prescrire international
Publication Date
Volume
8
Issue
44
Pages
183–187
Identifiers
PMID: 11503822
Source
Medline
License
Unknown

Abstract

(1) Some macrolides carry a strong risk of potentially severe drug interactions. (2) Erythromycin is the macrolide with the biggest risk of interactions. (3) Spiramycin is the macrolide with the smallest risk of interactions. Azithromycin and dirithromycin also seem to have a low risk of interactions, but they are far more recent and therefore less well known. (4) In first-line use, unless there are specific indications, a macrolide with a low risk of interactions should be used.

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