Choosing a macrolide: drug interactions must be taken into account.
- Published Article
- Publication Date
Dec 01, 1999
(1) Some macrolides carry a strong risk of potentially severe drug interactions. (2) Erythromycin is the macrolide with the biggest risk of interactions. (3) Spiramycin is the macrolide with the smallest risk of interactions. Azithromycin and dirithromycin also seem to have a low risk of interactions, but they are far more recent and therefore less well known. (4) In first-line use, unless there are specific indications, a macrolide with a low risk of interactions should be used.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11503822