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Chondroprotection and the prevention of osteoarthritis progression of the knee: a systematic review of treatment agents.

Authors
  • Gallagher, Brian
  • Tjoumakaris, Fotios P
  • Harwood, Marc I
  • Good, Robert P
  • Ciccotti, Michael G
  • Freedman, Kevin B
Type
Published Article
Journal
The American Journal of Sports Medicine
Publisher
SAGE Publications
Publication Date
Mar 01, 2015
Volume
43
Issue
3
Pages
734–744
Identifiers
DOI: 10.1177/0363546514533777
PMID: 24866892
Source
Medline
Keywords
License
Unknown

Abstract

For patients with or at risk for osteoarthritis, the use of glucosamine and chondroitin sulfate may serve as a nonoperative means to protect joint cartilage and delay osteoarthritis progression. Hyaluronic acid injections showed variable efficacy, while NSAIDs and vitamins E and D showed no effect on osteoarthritis progression. The other agents evaluated had no evidence in the literature to support or refute their use for chondroprotection.

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