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[Cholesterol esterase activity of human monocytes in ischemic heart disease].

Authors
  • Medvedeva, I N
  • Dolgov, A V
  • Nikitin, Iu P
Type
Published Article
Journal
Terapevticheskiĭ arkhiv
Publication Date
Jan 01, 1985
Volume
57
Issue
12
Pages
50–52
Identifiers
PMID: 4089769
Source
Medline
License
Unknown

Abstract

The comparison on the effect of atherosclerotic lesion of the vascular system on changes in the activity of human blood mononuclear cell lysosomal and cytoplasmic cholesterolesterases showed that these changes were of diverse nature an increase in lysosomal cholesterolesterase activity and a decrease in cytoplasmatic activity. It can be accounted for be a different role of acid and alkaline cholesteroesterases in cell cholesterol metabolism and by different mechanisms of the regulation of these enzymes.

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