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Cholesteatoma epithelium is characterized by increased expression of Ki-67, p53 and p21, with minimal apoptosis.

Authors
  • Huisman, Margriet A
  • De Heer, Emile
  • Grote, Jan J
Type
Published Article
Journal
Acta oto-laryngologica
Publication Date
Apr 01, 2003
Volume
123
Issue
3
Pages
377–382
Identifiers
PMID: 12737294
Source
Medline
License
Unknown

Abstract

Our results indicate that increased cell proliferation in cholesteatoma epithelium is accompanied by an increase in p53 and p21 protein levels, whilst apoptosis is minimal.

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