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Choice of Summary Statistic Weights in Approximate Bayesian Computation

Authors
  • Jung, Hsuan
  • Marjoram, Paul
Type
Published Article
Journal
Statistical Applications in Genetics and Molecular Biology
Publisher
Walter de Gruyter GmbH
Publication Date
Sep 27, 2011
Volume
10
Issue
1
Identifiers
DOI: 10.2202/1544-6115.1586
Source
De Gruyter
Keywords
License
Yellow

Abstract

In this paper, we develop a Genetic Algorithm that can address the fundamental problem of how one should weight the summary statistics included in an approximate Bayesian computation analysis built around an accept/reject algorithm, and how one might choose the tolerance for that analysis. We then demonstrate that using weighted statistics, and a well-chosen tolerance, in such an approximate Bayesian computation approach can result in improved performance, when compared to unweighted analyses, using one example drawn purely from statistics and two drawn from the estimation of population genetics parameters.

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