Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.
- Published Article
- Publication Date
Mar 01, 2001
In the SHRSP, (1) like cerebral microangiopathy, renal microangiopathy is selectively Cl(-) sensitive and hence, systemic microangiopathy is as well; (2) Cl(-) likely amplifies microangiopathy by exacerbating hypertension and possibly also by increasing PRA; and (3) Cl(-) might increase blood pressure and PRA by further constricting the renal afferent arteriole.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11231362