Affordable Access

Chemoprevention of breast cancer among Asian women--its perspective and problems.

Authors
  • Sasano, Hironobu
  • Suzuki, Takashi
Type
Published Article
Journal
Biomedicine & Pharmacotherapy
Publisher
Elsevier
Publication Date
Jul 01, 2006
Volume
60
Issue
6
Pages
266–268
Identifiers
PMID: 16860970
Source
Medline
License
Unknown

Abstract

Chemoprevention of breast cancer employing tamoxifen and others has been demonstrated to be effective in reducing the frequency of developing breast malignancy in Western countries. In Asian countries, the frequency of breast cancer as well as its premalignant lesions has recently increased. Therefore, the possible chemoprevention may benefit those women with potential high risks of developing breast cancer and with premalignant lesions. However, the details of these findings of chemoprevention in Western countries have not been available for women with Asian descendant. In addition, risk factors of developing breast cancer in healthy women have not been established in Asian countries compared to Western countries with relative paucity of familial breast cancer cases. Thus, possible chemoprevention of breast cancer in Asian countries may be targeted toward those with established premalignant breast lesions such as ductal carcinoma in situ and/or atypical ductal hyperplasia. However, due to their recent increment of their incidence, biological and/or clinical features of these premalignant breast lesions have not been extensively characterized in Asian women and further investigations are required for wide spread chemoprevention.

Report this publication

Statistics

Seen <100 times