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Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success.

Authors
  • Mehlotra, Rajeev K
  • Cheruvu, Vinay K
  • Blood Zikursh, Melinda J
  • Benish, Rebekah L
  • Lederman, Michael M
  • Salata, Robert A
  • Gripshover, Barbara
  • McComsey, Grace A
  • Lisgaris, Michelle V
  • Fulton, Scott
  • Subauste, Carlos S
  • Jurevic, Richard J
  • Guillemette, Chantal
  • Zimmerman, Peter A
  • Rodriguez, Benigno
Type
Published Article
Journal
The Journal of Infectious Diseases
Publisher
Oxford University Press
Publication Date
Jul 15, 2011
Volume
204
Issue
2
Pages
291–298
Identifiers
DOI: 10.1093/infdis/jir262
PMID: 21673041
Source
Medline
License
Unknown

Abstract

These findings suggest that CCR5 -2459G>A genotype had a strong, race-specific influence on TVLS in this cohort. Understanding the possible mechanisms underlying this influence requires further studies.

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