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ChemInform Abstract: Aurones: Interesting Natural and Synthetic Compounds with Emerging Biological Potential

Authors
Type
Published Article
Journal
ChemInform
Publisher
Wiley (John Wiley & Sons)
Publication Date
May 30, 2012
Volume
43
Issue
26
Identifiers
DOI: 10.1002/chin.201226228
Source
LBMCC
Keywords
License
White

Abstract

Aurones [2-benzylidenebenzofuran-3(2H)-ones] are either natural or synthetic compounds, belonging to the flavonoid family. They are isomeric to flavones and provide a bright yellow color to the plants in which they occur. Today, a literature survey indicates that the related flavonoids have been studied not only for their physiological properties and effects on Nature, but also for their therapeutic potential. Aurones are recently attracting the interest of an increasing number of research groups, and, since the last review, some interesting advances have been made in understanding the aurones. In this review, we report the recent advances made on the synthetic routes towards aurones. We also highlight their activity in different biological areas, as well as applied genetic plant modifications to produce these colored compounds. Their synthesis, structure–activity relationships and the importance of the substitution pattern will also be mentioned. Finally, some aspects regarding the possible development of aurones will be discussed briefly.

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