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Chemical modulation of glycerolipid signaling and metabolic pathways

Authors
  • Scott, Sarah A.
  • Mathews, Thomas P.
  • Ivanova, Pavlina T.
  • Lindsley, Craig W.
  • Brown, H. Alex1, 2, 3, 2, 4, 5, 6, 2, 7, 5
  • 1 Department of Pharmacology
  • 2 Vanderbilt University Medical Center
  • 3 Vanderbilt Center for Neuroscience Drug Discovery
  • 4 Department of Chemistry
  • 5 Vanderbilt University
  • 6 Department of Biochemistry
  • 7 Vanderbilt Institute of Chemical Biology
Type
Published Article
Journal
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Publisher
Elsevier
Publication Date
Jan 01, 2014
Accepted Date
Jan 07, 2014
Identifiers
DOI: 10.1016/j.bbalip.2014.01.009
Source
Elsevier
Keywords
License
Unknown

Abstract

•Glycerolipid-signaling pathways play an important role in human physiology and disease.•Glycerolipid-metabolizing enzymes are attractive targets for therapeutic intervention.•Chemical modulators interrupting glycerolipid signaling are essential tools in research.

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