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Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors.

Authors
  • St-Jacques, René
  • Toulmond, Sylvie
  • Auger, Anick
  • Binkert, Christoph
  • Cromlish, Wanda
  • Fischli, Walter
  • Harris, Jennifer
  • Hess, Patrick
  • Liu, Susana
  • Riendeau, Denis
  • Steiner, Beat
  • Percival, M David
Type
Published Article
Journal
Journal of the renin-angiotensin-aldosterone system : JRAAS
Publication Date
Sep 01, 2011
Volume
12
Issue
3
Pages
133–145
Identifiers
DOI: 10.1177/1470320310392618
PMID: 21393355
Source
Medline
License
Unknown

Abstract

Enalapril-pretreated dTG rats are suitable for long-term MAP monitoring and sequential evaluation of human renin inhibitors.

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