Affordable Access

Characterization of plasmids conferring resistance to gentamicin and apramycin in strains of Salmonella typhimurium phage type 204c isolated in Britain.

Authors
  • Threlfall, E J
  • Rowe, B
  • Ferguson, J L
  • Ward, L R
Type
Published Article
Journal
The Journal of hygiene
Publication Date
Dec 01, 1986
Volume
97
Issue
3
Pages
419–426
Identifiers
PMID: 3540111
Source
Medline
License
Unknown

Abstract

In Salmonella typhimurium phage type 204c isolated in Britain, gentamicin resistance is specified by plasmids of the I1 compatibility group which also confer resistance to apramycin. These plasmids have been subdivided into three types within the I1 group on the basis of their antibiotic resistance specificity, their ability to produce colicin Ib and their restriction enzyme digest fragmentation patterns. All three have been identified in strains from cattle, but as yet only two types have been found in strains from humans. It is suggested that the use of apramycin in animal husbandry is responsible for the appearance of gentamicin resistance in multiresistant strains of phage type 204c, a phage type already epidemic in bovine animals and with an increasing incidence in humans.

Report this publication

Statistics

Seen <100 times