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Characterization of human pericardial macrophages.

Authors
  • Benhaiem-Sigaux, N
  • Mina, E
  • Sigaux, F
  • Lambré, C R
  • Valensi, F
  • Allégret, C
  • Bernaudin, J F
Type
Published Article
Journal
Journal of leukocyte biology
Publication Date
Dec 01, 1985
Volume
38
Issue
6
Pages
709–721
Identifiers
PMID: 2415648
Source
Medline
License
Unknown

Abstract

This paper deals with the study of the cell population in 13 samples of normal human pericardial fluid. Large mononuclear cells (LMC) constituted 74.1 +/- 18.5% of the total cell population. These LMC possess the characteristics of macrophages firm adherence to glass intracytoplasmic presence of vimentin without keratin, ultrastructural observation of a lysosomal apparatus cytoenzymatic activities: acid phosphatases, naphthol AS.D acetate esterase and peroxidases, and phagocytosis of Baker's yeasts. All these data clearly show that macrophages are the main component of the pericardial fluid cell population and can be of great significance in the defense mechanisms and physiology of the pericardial space.

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