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[Characteristic CT findings in Krabbe's disease].

Authors
  • Yamanouchi, H1
  • Yanagisawa, T
  • Takahashi, M
  • Shimizu, S
  • Hatakeyama, S
  • 1 Department of Pediatric Neurology, Gunma Children's Medical Center.
Type
Published Article
Journal
No to hattatsu = Brain and development
Publication Date
Jan 01, 1990
Volume
22
Issue
1
Pages
77–81
Identifiers
PMID: 2294954
Source
Medline
License
Unknown

Abstract

In 12-month-old girl with Krabbe's disease, serial CT and MRI examinations showed characteristic findings, which were symmetric high densities in globus pallidus and thalami before and during the course of brain atrophy and decreased attenuation in white matter. The low densities in white matter were not so remarkable as other degenerative diseases affecting primarily white matter. The high densities in the globus pallidus changed into low densities with progression of the white matter hypodensities and brain atrophy. These findings on CT in Krabbe's disease may assist neurologists in narrowing the differential diagnosis and requesting appropriate laboratory tests.

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