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[Changes in fecal bile acid excretion after proctocolectomy].

Authors
Type
Published Article
Journal
Zeitschrift für Gastroenterologie
Publication Date
Volume
34
Issue
2
Pages
105–110
Identifiers
PMID: 8659184
Source
Medline
License
Unknown

Abstract

To study the effect of total colectomy for fecal bile acid excretion we examined groups of patients with ulcerative colitis and familial adenomatous polyposis coli 4,8 +/- 2.9 years after surgery. Patients after total colectomy showed a significant higher fecal bile acid excretion compared to healthy persons (mean +/- SD: 190.8 +/- 195.2 mumol/d). The highest fecal output occurred in patients with permanent ileostomies (mean +/- SD: 7595.0 +/- 5651.4 mumol/d), it was significantly higher compared to patients with ileoanal pouch anastomosis (mean +/- SD: 2212.8 +/- 2132.8 mumol/d). The daily fecal output of patients with ileorectal anastomosis (mean +/- SD: 4331.8 +/- 6314.7 mumol/d) is between the results of both other groups without any significance. After total colectomy only primary bile acids were found in each group whereas healthy people had almost identically rates of primary and secondary bile acids in their stools.

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