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Changes in Cerebellar Activation After Onabotulinumtoxin A Injections for Spasticity After Chronic Stroke: A Pilot Functional Magnetic Resonance Imaging Study.

Authors
  • Chang, Chia-Lin1
  • Weber, Douglas J2
  • Munin, Michael C3
  • 1 Department of Kinesiology, University of San Francisco, San Francisco, CA. Electronic address: [email protected]
  • 2 Defense Advanced Research Projects Agency, Arlington, VA.
  • 3 Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA.
Type
Published Article
Journal
Archives of physical medicine and rehabilitation
Publication Date
Nov 01, 2015
Volume
96
Issue
11
Pages
2007–2016
Identifiers
DOI: 10.1016/j.apmr.2015.07.007
PMID: 26239302
Source
Medline
Keywords
License
Unknown

Abstract

Reducing spasticity via Obtx-A injection may increase cerebellar activation both during gripping tasks with the paretic hand and during rest. To our knowledge, this is the first study that examines changes in cerebellar activation after spasticity treatment with Obtx-A.

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