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Immunizing properties of live attenuated measles virus

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Publication Date
Volume
57
Issue
1
Identifiers
DOI: 10.1016/s0022-3476(60)80208-9

Abstract

Summary Early clinical trials indicate that it is possible to immunize children with live attenuated measles virus. The susceptible subjects develop either no symptoms at all or a modified measles with fever, leukopenia, and a faint eruption. Koplik spots are uncommon. These children have no catarrhal symptoms and do not appear toxic. All of the susceptible children developed a significant titer of neutralizing antibodies. No complications occurred in any of our cases. The urgent need of a measles vaccine is stressed, and there are indications that measles immunization as a routine procedure may not be too distant.

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