Affordable Access

Synthesis and properties of biodegradable elastomeric epoxy modified polyurethanes based on poly(ε-caprolactone) and poly(ethylene glycol)

Authors
Journal
European Polymer Journal
0014-3057
Publisher
Elsevier
Publication Date
Volume
41
Issue
10
Identifiers
DOI: 10.1016/j.eurpolymj.2005.05.004
Keywords
  • Biodegradation
  • Polyurethanes
  • Epoxy Resins
  • Poly(ε-Caprolactone)
  • Poly(Ethylene Glycol)
Disciplines
  • Medicine

Abstract

Abstract Biodegradable polyurethane elastomers with potential for applications in medical implants with tunable degradation rate and physical properties were synthesized from reaction of epoxy terminated polyurethanes (EUP) with 1,6-hexamethylene diamine (HMDA) as curing agent. Poly( ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) as well as 1,6-hexamethylene diisocyanate (HDI) were used for preparation of isocyanate terminated polyurethanes which were subsequently blocked with glycidol to prepare EUPs. All materials were characterized by conventional methods, and their properties were studied fully. Results showed that elastomers based on PEG exhibit superior degradation rate and inferior mechanical properties in comparison to elastomers based on PCL. Optimum degradation rate and mechanical properties were obtained from elastomers made from mixture of PCL and PEG base EUPs.

There are no comments yet on this publication. Be the first to share your thoughts.