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Cerebrospinal fluid antibodies to tubulin are elevated in the patients with multiple sclerosis.

Authors
Type
Published Article
Journal
European journal of neurology
Publication Date
Volume
15
Issue
11
Pages
1173–1179
Identifiers
DOI: 10.1111/j.1468-1331.2008.02223.x
PMID: 18973612
Source
Medline
License
Unknown

Abstract

The estimation of anti-TU in CSF can contribute to the overall assessment of axonal damage; on the contrary serum anti-tubulin antibodies were not useful for differential purposes in MS. The antibodies to the neuron-specific portion of tubulin seemed to be synthesised predominantly intrathecally.

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