The estimation of anti-TU in CSF can contribute to the overall assessment of axonal damage; on the contrary serum anti-tubulin antibodies were not useful for differential purposes in MS. The antibodies to the neuron-specific portion of tubulin seemed to be synthesised predominantly intrathecally.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/18973612