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Cerebrospinal fluid antibodies to tubulin are elevated in the patients with multiple sclerosis.

Authors
  • Svarcová, J
  • Fialová, L
  • Bartos, A
  • Steinbachová, M
  • Malbohan, I
Type
Published Article
Journal
European journal of neurology
Publication Date
Nov 01, 2008
Volume
15
Issue
11
Pages
1173–1179
Identifiers
DOI: 10.1111/j.1468-1331.2008.02223.x
PMID: 18973612
Source
Medline
License
Unknown

Abstract

The estimation of anti-TU in CSF can contribute to the overall assessment of axonal damage; on the contrary serum anti-tubulin antibodies were not useful for differential purposes in MS. The antibodies to the neuron-specific portion of tubulin seemed to be synthesised predominantly intrathecally.

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