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Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction.

Authors
  • Kett-White, Rupert
  • Hutchinson, Peter J
  • Al-Rawi, Pippa G
  • Czosnyka, Marek
  • Gupta, Arun K
  • Pickard, John D
  • Kirkpatrick, Peter J
Type
Published Article
Journal
Journal of neurosurgery
Publication Date
Jun 01, 2002
Volume
96
Issue
6
Pages
1013–1019
Identifiers
PMID: 12066900
Source
Medline
License
Unknown

Abstract

The brain tissue PO2 decreases with hypotension, and, when it is below 8 mm Hg for longer than 30 minutes during temporary clipping, it is associated with increasing extracellular glutamate levels and cerebral infarction.

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