Affordable Access

Cerebral mucormycosis in diabetic mice after intrasinus challenge.

Authors
  • Waldorf, A R
  • Diamond, R D
Type
Published Article
Journal
Infection and immunity
Publication Date
Apr 01, 1984
Volume
44
Issue
1
Pages
194–195
Identifiers
PMID: 6706405
Source
Medline
License
Unknown

Abstract

Rhinocerebral involvement is the most common form of mucormycosis in uncontrolled diabetic patients. Streptozotocin-induced diabetic and normal mice were challenged by intrasinus inoculation of Rhizopus oryzae to determine their susceptibility to infection by this route. Ninety percent of diabetic mice and no normal mice died after inoculation with 10(6) spores. Intrasinus inoculations caused minimal direct trauma and low levels of brain inocula, but progressive cerebral infections were induced in diabetic mice.

Report this publication

Statistics

Seen <100 times