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[Cerebellar ataxia and hypogonadism. Description of 4 cases].

Authors
  • De Michele, G
  • Filla, A
  • Striano, S
  • Iorio, L
  • Merola, B
  • De Rosa, M
  • Lombardi, G
  • Campanella, G
Type
Published Article
Journal
Rivista di neurologia
Publication Date
Jan 01, 1987
Volume
57
Issue
6
Pages
328–332
Identifiers
PMID: 3330623
Source
Medline
License
Unknown

Abstract

We describe the association of cerebellar ataxia and hypogonadism in four female patients. Clinical, neurophysiological, neuroradiological and endocrinological features are reported. Post-mortem findings in one case are also described. We show in our patients that, beside the cerebellum, both the supratentorial white matter and the peripheral nerve are involved. We suggest that this association can be considered as a "multiple system atrophy". Furthermore, since hypogonadism is hypergonadotropic in three patients and hypogonadotropic in one, the endocrine pattern appears to be heterogeneous.

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