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Central pattern generators: some principles learned from invertebrate model systems.

Authors
  • Lukowiak, K
Type
Published Article
Journal
Journal de physiologie
Publication Date
Jan 01, 1991
Volume
85
Issue
2
Pages
63–70
Identifiers
PMID: 1757891
Source
Medline
License
Unknown

Abstract

1. Central pattern generators (CPGs) underlie a wide variety of rhythmic behaviours such as locomotion and respiration in most multi-cellular organisms. 2. The CPG's are capable of generating a patterned output without phasic sensory input. 3. The organization of the CPG is due to both intrinsic properties of the individual neurons and their network interactions. 4. To gain an understanding of the mechanisms which underlie rhythmicity a CPG has been reconstructed in culture. This will allow investigators to test directly the mechanisms underlying the generation of rhythmic output and will allow the direct testing of the mechanisms by which various modulators affect the CPG.

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