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Cellular distribution of Ca2+ pumps and Ca2+ release channels in rat cardiac hypertrophy induced by aortic stenosis.

Authors
  • Anger, M
  • Lompré, A M
  • Vallot, O
  • Marotte, F
  • Rappaport, L
  • Samuel, J L
Type
Published Article
Journal
Circulation
Publication Date
Dec 01, 1998
Volume
98
Issue
22
Pages
2477–2486
Identifiers
PMID: 9832495
Source
Medline
License
Unknown

Abstract

In severe hypertrophy, decreased accumulation of SERCA 2a was heterogeneous and not compensated by an induction of SERCA 2b in the cardiomyocytes. Decrease in RyR2 expression was more homogeneous and not compensated by an increased IP3R expression.

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