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Cell signalling and motility in Entamoeba histolytica.

Authors
Type
Published Article
Journal
Parasitology Today
0169-4758
Publisher
Elsevier
Publication Date
Volume
9
Issue
10
Pages
364–369
Identifiers
PMID: 15463670
Source
Medline

Abstract

Entamoeba histolytica crawls as a polarized cell following external stimuli, with the translocation of signals modifying extracellular matrix interactions and the amoeba cytoskeleton. Nancy Guillén here describes how the gliding of E. histolytica cells requires the activity of the actomyosin complex, and how actomyosin functions related to motility are necessary for pathogenesis and for amoebal escape from the host immune response.

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