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Celiac disease causing severe osteomalacia: an association still present in Morocco!

Authors
  • Tahiri, Latifa
  • Azzouzi, Hamida
  • Squalli, Ghita
  • Abourazzak, Fatimazahra
  • Harzy, Taoufik
Type
Published Article
Journal
Pan African Medical Journal
Publisher
Pan African Medical Journal
Publication Date
Jan 01, 2014
Volume
19
Pages
43–43
Identifiers
DOI: 10.11604/pamj.2014.19.43.2757
PMID: 25667705
Source
Medline
Keywords
License
Unknown

Abstract

Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated celiac disease. Osteomalacia complicating celiac disease had become more and more rare. We describe here a case of osteomalacia secondary to a longstanding untreated celiac disease. This patient complained about progressive bone and muscular pain, weakness, fractures and skeletal deformities. Radiological and laboratory findings were all in favor of severe osteomalacia. Improvement of patient's weakness and laboratory abnormalities was obvious after treatment with gluten free diet, vitamin D, calcium and iron. This case affirms that chronic untreated celiac disease, can lead to an important bone loss and irreversible complications like skeletal deformities.

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