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Trends affecting the future of vaccine development and delivery: The role of demographics, regulatory science, the anti-vaccine movement, and vaccinomics

Authors
Journal
Vaccine
0264-410X
Publisher
Elsevier
Publication Date
Volume
27
Identifiers
DOI: 10.1016/j.vaccine.2009.01.069
Keywords
  • Vaccinomics
  • Vaccine Future
  • Vaccine
  • Anti-Vaccine
  • Randomized Clinical Trials
  • Gene Polymorphisms
Disciplines
  • Biology
  • Communication
  • Medicine

Abstract

Abstract Important scientific, cultural, temporal, and secular issues impact the development of, and delivery of vaccines. In this paper we discuss the impact of demographics, regulatory science, the anti-vaccine movement, and finally the impact of the new biology and individualized medicine, which we call vaccinomics, on vaccine development and delivery. A description of the issues and how they have, are, or should be impacting vaccinology is provided, and hopefully will result in increased attention and discussion among vaccinologists. These issues have been under-valued, under-discussed, and in some cases, ignored. We hope that discussion of these issues will result in changes in how we develop, and how we communicate those developments, to the public.

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