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Compulsive attentive behavior after lesion of the ventral striatum in the cat: A behavioral and electrophysiological study

Authors
Journal
Experimental Neurology
0014-4886
Publisher
Elsevier
Publication Date
Volume
92
Issue
3
Identifiers
DOI: 10.1016/0014-4886(86)90310-9

Abstract

Abstract Bilateral lesions of the nucleus accumbens in cat elicited the following changes: perseveration in tests requiring focused attention, with difficulty to shift to other targets; paucity of movements, animals displaying moderate hypokinesia and loss of reaction to changes in the environment. These symptoms were accompanied by a significant increase in the amount of beta rhythms, an activity that has been shown to be concomitant with the development of focused attentive behavior. The observed behavioral and electrocortical modifications are opposite those that have been previously obtained in the same species after lesions of the ventral tegmental area.

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