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CDKN2A variants in a population-based sample of Queensland families with melanoma.

Authors
  • Aitken, J
  • Welch, J
  • Duffy, D
  • Milligan, A
  • Green, A
  • Martin, N
  • Hayward, N
Type
Published Article
Journal
Journal of the National Cancer Institute
Publication Date
Mar 03, 1999
Volume
91
Issue
5
Pages
446–452
Identifiers
PMID: 10070944
Source
Medline
License
Unknown

Abstract

CDKN2A mutations are rare in this population (approximately 0.2% of all melanoma cases in Queensland) and appear to be associated with melanoma in only the most affected families. The Nt500G allele appears to be associated with familial risk, but this association probably reflects Celtic ancestry.

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