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Hepatic fibrosis and survival in biliary atresia

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Volume
144
Issue
1
Identifiers
DOI: 10.1016/j.jpeds.2003.09.042

Abstract

Abstract In biliary atresia, progression of hepatic fibrosis before the Kasai portoenterostomy may explain why age is a major determinant of survival of the native liver. Blinded fibrosis scoring of surgical liver biopsies demonstrated that age and fibrosis correlate. Those biopsies with severe fibrosis predicted significantly worse survival.

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