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Diuretics: again the first step in the treatment of most patients with hypertension

Authors
Journal
Current Controlled Trials in Cardiovascular Medicine
1468-6708
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
2
Issue
5
Identifiers
DOI: 10.1186/cvm-2-5-244
Keywords
  • Review

Abstract

The results and interpretations of the most recent controlled clinical trials on antihypertensive drugs have fuelled the debate about the drug that should be used to begin treatment for hypertension. Every comparison of diuretics with other drugs has shown that the benefits of diuretics are equivalent to, or better than, other options. These findings, together with other practical reasons, such as left ventricular mass reducing effect, easy administration, few side effects and low cost, suggest that diuretics should regain their primacy as the first step in drug management of hypertension.

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