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Cd44: a marker of squamous differentiation in adenosquamous neoplasms.

Authors
  • Ylagan, L R
  • Scholes, J
  • Demopoulos, R
Type
Published Article
Journal
Archives of pathology & laboratory medicine
Publication Date
Feb 01, 2000
Volume
124
Issue
2
Pages
212–215
Identifiers
PMID: 10656728
Source
Medline
License
Unknown

Abstract

Our study shows that CD44(s) and its variants are good markers of squamous epithelial differentiation in several types of normal epithelium and tumors, and that these markers can identify areas of well- to moderately differentiated elements in adenosquamous neoplasms. However, poorly differentiated tumors show an inconsistent staining pattern with CD44, such that it cannot be used as a reliable and practical marker of squamous differentiation in poorly differentiated neoplasms.

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