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CD4+ lymphocytes are increased in the sinus mucosa of children with chronic sinusitis.

Authors
  • 1
  • 1 Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Pritzker School of Medicine, Ill, USA.
Type
Published Article
Journal
Archives of otolaryngology--head & neck surgery
Publication Date
Volume
122
Issue
10
Pages
1071–1076
Identifiers
PMID: 8859119
Source
Medline
License
Unknown

Abstract

Children with chronic sinusitis have predominance of CD4+ cells in the sinus mucosa as compared with normal sphenoid tissue. This contrasts with published results in adults with chromic sinusitis, in whom CD8+ cells predominate in nasal polyps and the submucosa, possibly reflecting a difference in the immunologic response of children and adults.

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