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CCL2, CXCL8, CXCL9 and CXCL10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees.

Authors
  • Bonfante, Herval de Lacerda1
  • Almeida, Caroline de Souza2
  • Abramo, Clarice2
  • Grunewald, Sabrine Teixeira Ferraz3
  • Levy, Roger Abramino4
  • Teixeira, Henrique Couto2
  • 1 Department of Pharmacology, Institute of Biological Sciences, Federal University of Juiz de Fora, Minas Gerais, Brazil. , (Brazil)
  • 2 Department Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Minas Gerais, Brazil. , (Brazil)
  • 3 Department of Maternal and Child Health, Faculty of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil. , (Brazil)
  • 4 Department of Rheumatology, Rio de Janeiro State University, Faculty of Medical Sciences, Rio de Janeiro, Brazil. , (Brazil)
Type
Published Article
Journal
International Journal of Rheumatic Diseases
Publisher
Wiley (Blackwell Publishing)
Publication Date
Dec 01, 2017
Volume
20
Issue
12
Pages
1958–1964
Identifiers
DOI: 10.1111/1756-185X.12589
PMID: 25955863
Source
Medline
Keywords
License
Unknown

Abstract

Hydroxychloroquine treatment did not alter the serum levels of CCL2, CXCL8, CXCL9 or CXCL10 in patients with OA of the knees, although increased serum levels correlated with aging for all subjects, including controls.

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