A multivariate paradigm, aimed at furthering the understanding of the factors underlying the devotion to practice of salaried primary care practitioners, has been developed and subjected to empirical verification. A study among a sample of Israeli primary care practitioners (N=134) revealed an empirical structure of 'Practice Compatibility', suggesting that the devotion to practice is conditioned by the clinical and professional role compatibility. Compatibility in turn is contingent on the practitioners' conviction in the sincerity of manifest health care oriented goals of the care-providing-framework. The herein developed notion of 'Practice Compatibility' facilitated the distinction between types of employing frameworks according to the factors predicting the salaried primary care practitioners' devotion to practice. In this respect the contribution of the present study is in identifying the factors underlying the salaried practitioners' motivation to practice. However, contrary to the expected, practice compatibility does not predict the primary care practitioners' likelihood to demonstrate affective behavior. Thus the data were unable to repudiate earlier evidence regarding the significance of the private fee-for-service framework in predicting affective behavior.