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Nucleotide sequence of the nfa A gene encoding the antigen 8786 adhesive factor of enterotoxigenicEscherichia coli

Authors
Journal
FEMS Microbiology Letters
0378-1097
Publisher
Oxford University Press
Publication Date
Keywords
  • Enterotoxigenicescherichia Coli
  • Adhesive Factor
  • Nucleotide Sequence
  • Escherichia Coli
Disciplines
  • Design

Abstract

Abstract The nucleotide sequence of a 714-bp DNA fragment containing the enterotoxic Escherichia coli (ETEC) adhesive factor 8786 structural gene, designated nfa A, revealed an open reading frame of 498 bp encoding a polypeptide of 166 amino acids. Primer-extension experiments showed that the nfa A gene is within a single transcription unit. No homology was found with the ETEC adhesive factors already sequenced. In contrast, a homology with Salmonella enteritidis fimbrin SEF 14 was observed.

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