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[Cavins: new sights of caveolae-associated protein].

Authors
  • Shi, Dan
  • Liu, Yan
  • Lian, Xin
  • Zou, Wei
Type
Published Article
Journal
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Publication Date
Nov 01, 2013
Volume
29
Issue
11
Pages
1531–1537
Identifiers
PMID: 24701818
Source
Medline
License
Unknown

Abstract

Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma membrane. Many researches show that caveolae are involved in cell signaling and transport. Caveolin-1 is the major coat protein essential for the formation of caveolae. Recently, several reports indicated that the other caveolae-associated proteins, Cavins, are required for caveola formation and organization. It's worth noting that Cavin-1 could cooperate with Caveolin-1 to accommodate the structural integrity and function of caveolae. Here, we reviewed that the relationship between Cavins and Caveolins and explore the role of them in regulating caveolae.

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