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Causes of chemoreduction failure in retinoblastoma and analysis of associated factors leading to eventual treatment with external beam radiotherapy and enucleation.

Authors
Type
Published Article
Journal
Ophthalmology
0161-6420
Publisher
Elsevier
Publication Date
Volume
111
Issue
10
Pages
1917–1924
Identifiers
PMID: 15465557
Source
Medline

Abstract

Chemoreduction failure in this article was defined as unresponsive or, more commonly, recurrent retinoblastoma. Older patient age, greater tumor thickness, presence of vitreous seeds and subretinal fluid at baseline, and retinal tumor recurrence after chemoreduction were factors associated with the need for enucleation.

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