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Cationic surfactants-modified natural zeolites: improvement of the excipients functionality.

Authors
  • Krajisnik, Danina
  • Milojević, Maja
  • Malenović, Anđelija
  • Daković, Aleksandra
  • Ibrić, Svetlana
  • Savić, Snezana
  • Dondur, Vera
  • Matijasević, Srđan
  • Radulović, Aleksandra
  • Daniels, Rolf
  • Milić, Jela
Type
Published Article
Journal
Drug Development and Industrial Pharmacy
Publisher
Informa UK (Taylor & Francis)
Publication Date
Oct 01, 2010
Volume
36
Issue
10
Pages
1215–1224
Identifiers
DOI: 10.3109/03639041003695121
PMID: 20367087
Source
Medline
License
Unknown

Abstract

In vitro release profiles of the drugs from the zeolite-surfactant-drug composites revealed that sustained drug release could be attained over a period of 8 hours. The presented results for drug uptake by surfactant-zeolite composites and the afterward drug release demonstrated the potential use of investigated modified natural zeolite as excipients for advanced excipients in drug formulations.

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