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Cathepsin D in invasive ductal NOS, medullary, lobular and mucinous breast carcinoma. An immunohistochemical study.

Authors
  • Bedner, E
  • Harezga, B
  • Osborn, M
  • Domagała, W
Type
Published Article
Journal
Polish journal of pathology : official journal of the Polish Society of Pathologists
Publication Date
Jan 01, 1995
Volume
46
Issue
1
Pages
11–15
Identifiers
PMID: 7780691
Source
Medline
License
Unknown

Abstract

Cathepsin D expression was determined by immunohistochemistry in 445 formalin fixed, paraffin embedded primary invasive breast carcinomas. We found: 1. a relationship between cathepsin D expression and histological type of tumour, 2. a negative correlation between cathepsin D expression and histological grade, 3. a negative correlation between cathepsin D expression and tumour diameter, 4. a relationship between the morphology of cathepsin D granules and histological type of the tumour.

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