Abstract : Background:In urinary tract infections (UTI), one of the main types of nosocomial infections, indwelling catheters are present in 80-90% of the cases.Objectives: To determine the incidence and risk factors for cUTI in an intensive care unit (ICU) of a university hospital (UH).Method: Historical cohort, based on hospital records, conducted from 2011 to 2013, in an adult ICU of a UH in Southern Brazil. The sample consisted of 1394 patients who underwent indwelling urinary catheterization from a total of 2140 patients hospitalized during that period. Results: The cUTI incidence density rate was 6.56 per 1000 catheters/day. The chance of an elderly patient (=60 years) developing infection was 1.827 (OR) [?2=5.953; p=0.015]. Linear regression analysis showed that duration of catheterization (DC) was determinant for infection [Student's t test = 7.110; CI=95%; p=0.000], with length of hospital stay showing no influence [Student's t test =-1.133; CI=95%; p=0.257]. There was a relation between DC and cUTI both for clinical and surgical patients [F=166.166; p=0.000, and F=157.108; p=0.000, respectively]. Being male reduced the risk of infection [?2=4.02; p=0.045; CI=95%; OR=0.61]. Conclusion: The incidence density is within international standards; DC and age = 60 years are relevant risk factors; and being male is a protection factor.