Catecholamine contents in non-stimulated and pilocarpine-stimulated submaxillary salivary gland tissue (SGT), oral mucosa (OM) and stimulated saliva in acute staphylococcal inflammation of soft oral cavity tissue were determined in rats using the standard HPLC method. It was shown that 2 hrs after toxin injection NA contents decreased in non-stimulated SGT. After 24 hrs A contents decreased too as well as HA contents in OM. After 2 and 24 hrs HA contents increased in stimulated SGT, in OM HA contents did not change but A contents after 24 hrs decreased. In saliva, after 24 hrs these levers were normalized. The authors concluded that the inflammatory process in the soft oral cavity tissue was the cause of basal and stimulated salivary secretion disturbance.