Affordable Access

Caspofungin-resistant Aspergillus flavus after heart transplantation and mechanical circulatory support: a case report.

Authors
  • Eschertzhuber, S
  • Velik-Salchner, C
  • Hoermann, C
  • Hoefer, D
  • Lass-Florl, C
Type
Published Article
Journal
Transplant Infectious Disease
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jun 01, 2008
Volume
10
Issue
3
Pages
190–192
Identifiers
PMID: 17605738
Source
Medline
License
Unknown

Abstract

Invasive aspergillosis (IA) is a severe complication in the post-transplant period in recipients of solid organs. Therefore, early diagnosis and specific therapy of fungal infections in these patients are indispensable. We report the case of a 49-year-old patient, who suffered from IA after cardiac transplantation, which was complicated by post-transplant right heart failure requiring mechanical circulatory support using veno-arterial extracorporeal membrane oxygenation and a right ventricular assist device. Despite antifungal treatment, the patient died 3 weeks after transplantation because of multi-organ failure secondary to IA. The isolated Aspergillus strains exhibited in vitro resistance to caspofungin.

Report this publication

Statistics

Seen <100 times