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A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome.

Authors
  • Okoh, Helen Chioma
  • Lubana, Sandeep Singh
  • Langevin, Spencer
  • Sanelli-Russo, Susan
  • Abrudescu, Adriana
Type
Published Article
Journal
Case Reports in Rheumatology
Publisher
Hindawi Limited
Publication Date
Jan 01, 2015
Volume
2015
Pages
528026–528026
Identifiers
DOI: 10.1155/2015/528026
PMID: 26366317
Source
Medline
License
Unknown

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune systemic disease with multiple organ involvement with high morbidity and mortality rate. Among the severe potential fatal complications are those of the central and peripheral nervous system which usually develop during the course of the disease and very rarely from the outset of the disease. We are reporting a rare case of Miller-Fisher (MFS) variant of Guillain-Barré syndrome (GBS) as the first manifestation of SLE in a 41-year-old female who progressed to flaccid paralysis with no neurological improvement with initial immunosuppressive therapy, plasmapheresis, and first cycle of intravenous immunoglobulin (IVIG) but with remarkable and complete recovery after the second 5-day course of IVIG.

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