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[Case of suspected malignant hyperthermia following local infiltration anesthesia].

Authors
  • Kamitani, Kazuo
  • Yoshida, Hitoshi
  • Arai, Riho
  • Matsuura, Koso
  • Miyoshi, Harumi
  • Kuroda, Yasuko
Type
Published Article
Journal
Masui. The Japanese journal of anesthesiology
Publication Date
Aug 01, 2012
Volume
61
Issue
8
Pages
866–868
Identifiers
PMID: 22991814
Source
Medline
License
Unknown

Abstract

A 49-year-old man with no past history of malignant hyperthermia (MH) and scheduled for hernia repair was suspected of MH after local infiltration anesthesia at other hospital. Although intravenous diazepam was not effective for increased body temperature, tachycardia, and convulsion, dantrolene was effective for these signs. However, blood test showed no abnormal finding. At our hospital, he was scheduled for hernia repair and muscle biopsy under total intravenous anesthesia. No event occurred intra- and postoperatively. The examination for muscle biopsy revealed that the function of his ryanodine receptor 1 is abnormal. The events which had occurred at other hospital were uncertain of being associated with MH.

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