Affordable Access

Access to the full text

A case of invasive aspergillosis in CGD patient successfully treated with Amphotericin B and INF-γ

Authors
  • Mamishi, Setareh1
  • Zomorodian, Kamiar1, 2
  • Saadat, Farshid3
  • Gerami-Shoar, Mohsen1
  • Tarazooie, Bita1, 2
  • Siadati, Seyad Ahmad1
  • 1 Tehran University of Medical Sciences, Department of Infectious Diseases, Children Medical Center, Tehran, Iran , Tehran
  • 2 Tehran University of Medical Sciences, Department of Medical Mycology & Parasitology, School of Public Health and Institute of Public Health Research, Tehran, Iran , Tehran
  • 3 Tehran University of Medical Sciences, Department of Immunology, School of Public Health and Institute of Public Health Research, Tehran, Iran , Tehran
Type
Published Article
Journal
Annals of Clinical Microbiology and Antimicrobials
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Mar 03, 2005
Volume
4
Issue
1
Identifiers
DOI: 10.1186/1476-0711-4-4
Source
Springer Nature
Keywords
License
Yellow

Abstract

BackgroundChronic granulomatous disease (CGD) is a rare disorder of phagocytes in which absence of superoxide and hydrogen peroxide production in phagocytes predisposes patients to bacterial and fungal infections. The most common fungal infections in these patients are caused by Aspergillus species.Case presentationHere, we describe Aspergillus osteomyelitis of the ribs and hepatic abscess in a 5-year-old boy. The patient was successfully treated with Amphotericin B and INF-γ.ConclusionWith respect to the high frequency of aspergillosis in the CGD patient, immune deficiency should be investigated in patients with invasive aspergillosis. Moreover, using antifungal drugs as prophylaxis can improve the quality of life in these patients.

Report this publication

Statistics

Seen <100 times